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dc.contributor.authorRabbaa Khabbaz, Lydia
dc.contributor.authorHajj, Aline
dc.contributor.authorHallit, Souheil
dc.contributor.authorEl-Khatib, Rouba
dc.date.accessioned2023-05-16T06:09:22Z
dc.date.available2023-05-16T06:09:22Z
dc.date.issued2022-07-01
dc.identifier.citationHajj A, Hallit S, El-Khatib R, Abi Haidar S, Hajj Moussa Lteif F, Hajj L, Moudawar M, Rabbaa Khabbaz L. Pre-, Peri-, and Neonatal Factors Associated with Autism Spectrum Disorder: Results of a Lebanese Case-control Study. Innov Clin Neurosci. 2022 Jul-Sep;19(7-9):22-27.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.14131/834
dc.description.abstractObjective: The prevalence of autism spectrum disorder (ASD) in Lebanon is higher than what is reported by the World Health Organization (WHO), leading to the thought that the Lebanese population has some specific risk factors for ASD. Therefore, it is important to conduct more robust studies on this population. We conducted this study to identify pre-, peri-, and neonatal risk factors for ASD. Our ultimate goal was to detect and change some modifiable risk factors, thus reducing the incidence of ASD. Design: A case-control study was conducted using a random proportional sample of Lebanese children with ASD to explore whether risk factors, such as family history, pregnancy (including all medication and substances taken during pregnancy and infection history), gestational age, delivery, birth milestones, and the neonate's condition at birth could be associated with a higher prevalence of ASD. The local ethical committee approved the study (USJ-2016-91), and all parents gave their written consent. Results: A total of 66 children with ASD and 66 controls were included. The results of the multivariable analysis showed that a higher gestational weight gain (adjusted odds ratio [ORa]: 1.11) was significantly associated with higher odds of autism, whereas female sex (ORa: 0.13) and higher number of weeks of gestation (ORa: 0.76) were significantly associated with lower odds of autism. Conclusion: Such results are of great relevance, since many of the identified factors herein could be avoidable or modifiable, suggesting the need for implementing timely and appropriate public health strategies for disease prevention in pregnant women that could reduce ASD.en_US
dc.subjectAutism spectrum disorder; case-control study; gestational weight gain; pregnancy; risk factors.en_US
dc.titlePre-, Peri-, and Neonatal Factors Associated with Autism Spectrum Disorder: Results of a Lebanese Case-control Studyen_US
dc.source.journalInnov Clin Neuroscien_US
refterms.dateFOA2023-05-16T06:09:22Z
dc.contributor.researcherExternal Collaborationen_US
dc.contributor.labNAen_US
dc.subject.KSAPSYen_US
dc.contributor.ugstudent0en_US
dc.contributor.alumnae0en_US
dc.source.indexScopusen_US
dc.source.indexOther indexen_US
dc.contributor.departmentPsychologyen_US
dc.contributor.pgstudent0en_US
dc.contributor.firstauthorHajj, Aline


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