Impulsivity as a predictor of clinical and psychological outcomes in a naturalistic prospective cohort of subjects at ultra-high risk (UHR) for psychosis from Tunisia
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Author
Fekih-Romdhane, FetenGhrissi, Farah
Abassi, Bouthaini
Loch, Alexandre
Cherif, Wissal
Damak, Rahma
Ellini, Sana
Cheour, Majda
Hallit, Souheil
Subject
Psychosis; Impulsivity; Ultra-high risk; Outcomes; Quality of life; Psychological distress; TunisiaDate
2024-08-07
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Background: Impulsivity is associated with serious detrimental consequences on physical, mental, behavioral and social aspects of health among patients with psychosis. The present prospective 12-month follow-up study aimed to determine the prevalence of highly impulsive individuals among Ultra High Risk (UHR) patients, how impulsivity evolves over the follow-up period, and whether impulsivity impacts clinical, psychological and functional outcomes in this population. Method: UHR patients were invited to complete a battery of measurements at three-time points: at baseline, and at 6 and 12 months of follow-up. Impulsivity was assessed using both behavioral (the Wisconsin Card Sorting Test, WCST) and self-report (the Barratt Impulsiveness Scale, BIS-11) measures. Results: Findings showed that at 6 months of follow-up, higher 6-month BIS-11 attentional and motor impulsivity were significantly associated with lower quality of life and greater general psychological distress. In addition, higher baseline BIS-11 motor impulsivity significantly predicted more severe positive psychotic symptoms at 12 months of follow-up. However, WCST scores did not show any significant associations with study variables at the different times of follow-up. Conclusion: Interventions targeting impulsivity in UHR individuals could help decrease psychological distress and positive psychotic symptoms’ severity, as well as improve quality of life in UHR individuals.Department
PsychologyJournal title
Psychiatry Researchae974a485f413a2113503eed53cd6c53
10.1016/j.psychres.2024.116090